. I made some chicken and rice. I've read that simparica takes 35 days to get out of their system. Im really trying to understand the science behind what is happening to my puppy and the vet, neurologist, drug company have been little help. And yeah he ate today 4 chicken breast and appeared to want it even better. Company asked us to do diagnostic testing at vet. We go for more bloodwork today and are praying for better news. What Are The Side Effects Of Simparica Trio For Dogs? If she recovers, cause is the Simparica. Simparica Trio is the first and only product that combines sarolaner, moxidectin, and pyrantel in one simple-to-give chewablefor protection against: . I am so mad at the vet and think we should file suit against this company. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a . 1 is pregnant I told the vet what can I give the pregnant yorkie she said sampirica sold me a 3 month supple for her. Really angry this drug is on the market and pushed by many vets. I looked up side effects for this drug and was horrified to find that the flea med can cause tremors seizures and worse. He seems sometimes anxious and is sensitive to noise outside. Charlie took the pill on Monday and could not even walk this morning. Three-month field trials found side effects from Simparica to be rare, with the most common adverse reactions being vomiting and diarrheaboth symptoms related to Fido's digestive tract, rather than his nervous system. My one year old has severe diarrhea and is very agitated and anxious. Does any one think this could be a reaction to Simparico Trio? Im petrified after reading the comments here. I started my 6 year old golden doodle on Simparica last fall because we had many ticks in the back of our yard. Her last dose of Simparica Trio was given to her on October 1, 2021. Revolution has been around decades with less incidents of animal reactions. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. It seems to be clearing up with Rx eye drops. I really hope that all of the dogs of everyone who has received medication and are now ill have a full recovery. She never did that before! I gave my black lab mix Simparica for the 1st time on 4/1. Please think these things through before subjecting your pet to internal insecticides. Took a dose of simparica trio.second rose in second month.dog is having tremors. Simparica Trio works to prevent heartworm disease, treat and prevent flea infestations, treat and control tick infestations, and treat and control roundworms and hookworms. When he lays in the sun you can see the bumps under his skin. She has been on our property for four year and has survived everything. I'll continue to watch her. I'm at a loss We had same issues. I hope there will be a class action lawsuit but most importantly that the word get out to stop this medication from harming another life. Simparica Trio is just one of many parasite prevention products on the market for dogs. Over time, I spent 7k to save here but to no avail. Our dog has not been given another dose. and you expect people to give this to their beloved pets? Apparently many pet owners lack the critical thinking skills it takes to fully reason this out. Side effects include: vomiting, diarrhea, lethargy, anorexia, otitis externa (ear. We have an appt for a skin scraping. Hope all is well. I've tried Gatorade and Ginger ale but he only drank a little. Im still confused. Hope your pup is doing better!! Very "out of it". And im so mad that my vet didn't inform me of the side effects and im so mad I didn't research it myself. Now that Ive read all these comments I think he has developed these issues because of this trio medication. Today shes acting better, finally, but her back legs are still collapsing and she is weak. I called our Vet on the second day and they said they doubted very seriously that the Simparica would have give him diarrhea, and then told me that I should wait and see what happens with the next dose, because I had also told them that he had some drippings from some ground beef over his dog food the day before I gave him that first dose. My 1.5 yr old German Shepherd was a happy, playful healthy dog until this Poison and now I blame myself for what she is going through. They did a blood test (this is literally 7 days later) and his ATL liver levels were off the charts at >2000. I hope this drug has not caused permanent damage. He was in excellent health prior to this incident. I can tell something is off with her I just couldnt figure it out. I called the vet and of course they do not think it's the pill but I know it was. My vet is aware of this and prescribed simparica. I am more than upset, I am effing pissed, my poor little boy. old . Called his vet and they gave no information. The active ingredient of Simparica, sarolaner, belongs to a newer class of flea and tick preventatives called isoxazolines. , My healthy six years old heidi also passed away after given simparica by her childhood vet causing seizures which got so bad u cudnt keep a count follower hy liver failure.dont give ny tick fleas medication orally. (145 Reviews) $15.50 - $31.09. Also vets needs to tell the truth!!! We were told the Neurologist would be between $10,000 to $12,000. I have my 14 week old pup simparica (vet recommended) 2 days ago. Just gave my baby her first dose. Very dissapointed with my vet for not informing me of the risk this has on my dog. I called the breeder, and she said some vaccines and heartworm meds can cause neurological issues. The Trio product by Simparica is a three-in-one medication to control and prevent flea, tick, and heartworm. Simparica TRIO is a monthly chewable tablet that protects your dog against heartworm disease, five types of ticks, fleas, roundworms and hookworms. I took him to the ER they checked his vitals and sent me home. The following morning he had another small seizure. After he was sent home, he was still not well and barely able to hold in any food and had to take any fluids intravenously. Let us now look at possible side effects when administering Simparica. In clinical trials, vomiting and diarrhea were the most frequently reported adverse reactions. Use with caution in dogs with a history of seizures or neurologic disorders. I called the manufacturer (Zoetis) and filed a report, immediately discontinued the tablets and started to detox him. It went away, I thought the diarrhea was from some of the junk she eats off of the ground. Yea so what about the 10 percent? They are monitoring her. Hi there, my dog has been taking simparica trio for two months. I took him to the energy vet in the morning, he couldnt find any cause for pain, only he yelped a bit on his neck, they had trouble getting him in, he was yanking his neck around as he is afraid of the vet since getting fixed. How do I get this out of his system and what are you using instead? I'll be calling them tomorrow. The vet said not to give it. Also I read on Dr Mercola site that heartworms is in the dogs blood not the digestive track and garlic won't work. Went to a different vet, within minutes he found a large mass on my Poms abdomen. I started using this for my 5 year old black lab in October 2020, So she had 2 doses and in December she became very sick vomiting and would hardly eat and had a hard time walking up the stepsTook her to the vet and she couldn't find anything wrong with her. He took simparica trio 3 weeks ago and I cant wait until its out of his system! I am convinced this medicine is HORRIBLE and is causing this. How common are Simparica side effects? I thought the first one it happened to may have gotten something in her eye but then a few days later the other had the same issue. These are the side effects that were observed: Most common is vomitting Weakness and lethargy Soft stools Loss of appetite He also had a seizure that lasted for about 2 minutes in the middle of the night about 2 months ago and it was the most horrifying thing to watch and feel so helpless. Can you tell me if your dog is back to normal now?!?! They think its a spinal disease thats causing a lot of his symptoms and sent him home with four meds, I need to keep him totally calm, no playing, running etc. Our pick for best oral flea control product for dogs is Simparica TRIO, a chewable tablet that is fast-acting and kills more parasites than any other oral product. We took him to a emergency Vet Hospital that pin pointed Simparica Trio as the main facture that triggered his controlled seizure episodes in having constant all day tremors & seizures hurting him to the point of making the decision to put him down or have him continue with the pain until it killed him. The term off-label or extra-label use means that a medication is used in a way or in a particular species that is not specified on the medication label. This was the only thing we changed, I am convinced this is what did it to her. The FDA continues to monitor adverse drug event reports for these products and encourages pet owners and veterinarians to report adverse drug events. Use a collar or topical if you need to. Exactly. I am taking them both off Simparica. I wish I could get it out of her system. Our 6 year old, 66# Treeing Walker Coon Hound baby has been taking Simparica for about two years. Was hospitalized for 2 1/2 days. Then gave me pills of prednisone for him to take 1 pill twice a day . Will be back at PetSmart on Monday. Always confirm storage temperatures by reading the label. My 9 month old puppy started acting very lethargic after taking simparica trio. Pyrantel pamoate is a nematocide (kills some worms) belonging to the tetrahydropyrimidine class. only 7 yrs old and I still considered a puppy b/c of how active he was, we are on 8 days now of the lethargic not eating, goopy eyes - Dr says he has hyernaited disc but I have yet to see the xrays to confirm - blood work came back normail. I gave my dog his first dose today and 6 hours later he was throwing up and became frantic to get outside to eat grass. Just wondering? Never again will I be giving my pets any pharma meds. Then the following week 1 pill every other day . My chihuahua was given this three weeks back, I actually requested I kept my old treatment but they assured me it was safe and good. One common alternative is to give Heartgard for heartworms and intestinal parasites along with Bravecto to prevent fleas and ticks, but there are other choices out there. Contact your vet if your dog misses a month or more of heartworm preventionyour dog might have become infected with heartworm larvae. You can do this by reporting to the drugs manufacturers, who are required to report this information to the FDA, or by submitting a report directly to the FDA. All three drugs are pesticides that work by attacking the nervous system of the fleas and ticks, causing death. I lost my dog due to Simparica Trio. I disagree. He is not the same puppy prior to two days ago! $37.98 with Subscribe & Save discount. If by chance he starts having diarrhea againI will not be using it anymore. But few people read it or think it must be a million to one problem. He licks his lips all the time? I feel so sad for you Camelia. I just gave my Matty her first dose. 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